AB5603A4 Display Image

Anti-Sox2; Alexa Fluor 488 Conjugate

Code: AB5603A4 D2-231

Analysis Note

ControlUndifferentiated ReNcell VM neural progenitor cells

Application

Research Sub CategoryTranscription Factors

Detect Sox2...


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Your Price
€560.00 EACH

Analysis Note

ControlUndifferentiated ReNcell VM neural progenitor cells

Application

Research Sub CategoryTranscription Factors

Detect Sox2 using this Anti-Sox2, Alexa Fluor 488 Conjugate Antibody validated for use in ICC.

Research CategoryNeuroscience

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

SOX2 is also known as SRY related HMG BOX gene 2. All SOX proteins have a single HMG box and bind linear DNA in a sequence-specific manner, resulting in the bending of DNA through large angles. Bending causes the DNA helix to open for some distance, which may affect binding and interactions of other transcription factors. SOX1, SOX2 and SOX3 show the closest homology to SRY. They share maximum homology within the HMG domain and are expressed mainly in the developing nervous system of the mouse. These genes share significant homology outside the HMG box also and are highly conserved throughout their evolution.

Immunogen

Synthetic peptide from human Sox2.

Legal Information

ALEXA FLUOR is a registered trademark of Life Technologies

Physical form

Affinity purified

Purified rabbit polyclonal conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Quality

Evaluated by Immunocytochemistry in undifferentiated ReNcell VM neural progenitor cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Sox2 in undifferentiated ReNcell VM neural progenitor cells.

Storage and Stability

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Target description

The unconjugated antibody (AB5603) tested on western blot detects Sox2 in whole cell or nuclear extracts as a protein band at 34 kDa

antibody formaffinity isolated antibody
antibody product typeprimary antibodies
biological sourcerabbit
clonepolyclonal
conjugateALEXA FLUOR® 488
Gene Informationhuman ... SOX2(6657)
NCBI accession no.NP_003097
Quality Level100
shipped inwet ice
species reactivity (predicted by homology)mouse (based on 100% sequence homology)
species reactivityhuman
technique(s)immunocytochemistry: suitable
UniProt accession no.P48431
Quantity
Est. Dispatch/Availability