Application
Research Sub CategorySignaling Neuroscience
Research CategoryNeuroscience
Anti-SR-25 Antibody, clone 1F6.1 is a highly specific mouse monoclonal antibody, that targets SRp25 & has been tested in western blotting & ICC.
Immunocytochemistry Analysis: A 1:50 dilution from a representative lot detected SR-25 in HeLa cells treated with Mimosine and Nocodazole.
Dylight® is a registered trademark of Thermo Fisher Scientific.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Also known as ADP-ribosylation factor-like factor 6-interacting protein and ARL6IP4, the SR-25 protein is expressed in certain human organs and is relatively abundant in human testis and thymus. It is observed to mediate the Rac1 signaling pathway and acts as a splicing inhibitor of the Herpes simplex virus (HSVI); however, further research is needed to elucidate its mode of action.
Immunogen
GST-tagged recombinant protein corresponding to the C-terminus of human SR-25.
Legal Information
DyLight is a registered trademark of Pierce Biotechnology, Inc.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified
Format: Purified
Quality
Evaluated by Western Blotting in HeLa cells treated with Mimosine and Nocodazole.
Western Blotting Analysis: 1 µg/mL of this antibody detected SR-25 in HeLa cells treated with Mimosine and Nocodazole.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Target description
~32 kDa observed. Uniprot describes six isoforms between 22 kDa and 38 kDa
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