Anti-PPIF

Code: AV46141-100UL D2-231

Application

Anti-PPIF antibody produced in rabbit is suitable for western blotting at a concentration of 5µg/ml.

Biochem/physiol Actions

PPI...


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€396.00 100UL
€487.08 inc. VAT

Application

Anti-PPIF antibody produced in rabbit is suitable for western blotting at a concentration of 5µg/ml.

Biochem/physiol Actions

PPIF (peptidylprolyl isomerase F) also referred to as CypD or cyclophilin F belongs to peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases are highly-conserved cytoplasmic enzymes that accelerate protein folding. PPIF is a part of the mitochondrial permeability transition pore (mPTP) in the inner mitochondrial membrane. Hence, it is anticipated that its association with the mPTP masks the binding site for inhibiting inorganic phosphate (Pi) as well as enhances the open possibility of mPTP that results in apoptosis or necrosis.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Synthetic peptide directed towards the middle region of human PPIF

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: GSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLS

antibody formIgG fraction of antiserum
antibody product typeprimary antibodies
biological sourcerabbit
clonepolyclonal
concentration0.5 mg - 1 mg/mL
conjugateunconjugated
formbuffered aqueous solution
Gene Informationhuman ... PPIF(10105)
mol wt19 kDa
NCBI accession no.NP_005720
Quality Level100
shipped inwet ice
species reactivityguinea pig, human, rat, dog, horse, mouse, rabbit, bovine
storage temp.−20°C
technique(s)western blot: suitable
UniProt accession no.P30405
This product has met the following criteria to qualify for the following awards:



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