Biochem/physiol Actions
Cell permeable: no
Reversible: no
Primary TargetAntileukemic and immunosuppressive activity
Product does not compete with ATP.
General description
A deoxyadenosine analog that displays strong antileukemic and immunosuppressive activity. Also induces apoptosis in chronic lymphocytic leukemia (CLL) cells.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Bellosillo, B., et al. 1997. Blood 89, 3378; Bryson, H.M., and Sorkin, E.M. 1993. Drugs 46, 872.Robertson, L.E., et al. 1993. Blood81, 143.Carson, D.A., et al. 1988. Adv. Enzyme Regul. 27, 395.Carson, D.A., et al. 1984. Proc. Natl. Acad. Sci. USA 81, 2232.
Packaging
10 mg in Plastic ampoule
Warning
Toxicity: Harmful & Carcinogenic / Teratogenic (E)
This product has met the following criteria to qualify for the following awards: