Biochem/physiol Actions

Reversible: no

Primary TargetCa2+-dependent protein kinase C

Product does not compete with ATP.

Cell permeable: yes

General description

Note: 1 set = 10 x 500 µg.

Cell-permeable diacylglycerol analog that activates Ca²⁺-dependent protein kinase C. Also a stimulator of secretion and aggregation in blood platelets.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Florin-Christensen, J. 1993. Biochem. J.289, 783.Benz, I., et al. 1992. J. Membr. Biol. 130, 183.Haeffner, E.W., and Wittmann, U. 1992. J. Lipid Mediat.5, 237.Gilmore, T., and Martin, G.S. 1983. Nature306, 487.

Packaging

1 set in Glass bottle

5, 25 mg in Plastic ampoule

Reconstitution

Unstable in solution; reconstitute just prior to use. The material can be dissolved in chloroform, aliquoted, dried under a stream of nitrogen, and stored at -20°C.

Warning

Toxicity: Standard Handling (A)