#-SECRETASE INHIBITOR III 1PC X 500UG

Code: 565780-500UG D2-231

Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetBACE

Effective concentration: 5 µM com...


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€251.60 EACH
€309.47 inc. VAT

Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetBACE

Effective concentration: 5 µM completely blocking the proteolytic activity of β-secretase (BACE) in solubilized membrane fractions from BACE transfected MDCK cells

General description

A substrate analog inhibitor of β-secretase (BACE) that completely blocks proteolytic activity in solubilized membrane fractions of BACE-transfected MDCK cells at a concentration of 5 µM.

A substrate analog inhibitor of β-secretase (BACE) that completely blocks the proteolytic activity (at 5 µM) in solubilized membrane fractions from BACE transfected MDCK cells.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Capell, A., et al. 2002. J. Biol. Chem.277, 5637.Tung, J.S., et al. 2002. J. Med. Chem.45, 259.

Packaging

Packaged under inert gas

500 µg in Plastic ampoule

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Sequence

H-Glu-Val-Asn-Statine-Val-Ala-Glu-Phe-NH₂

Warning

Toxicity: Standard Handling (A)

assay≥95% (HPLC)
formlyophilized
manufacturer/tradenameCalbiochem®
Quality Level100
shipped inambient
solubilityDMSO: 1 mg/mL
storage conditiondesiccated (hygroscopic), OK to freeze
storage temp.−20°C
Cas Number552337-94-7
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