LETROZOLE EUROPEAN PHARMACOPOEIA (EP) R

Code: Y0000685 D2-231

Biochem/physiol Actions

Letrozole is a third generation nonsteroidal aromatase inhibitor. It is a competitive inhibitor of the aromatase enzyme system and thus inhibits the c...


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Biochem/physiol Actions

Letrozole is a third generation nonsteroidal aromatase inhibitor. It is a competitive inhibitor of the aromatase enzyme system and thus inhibits the conversion of androgens to estrogens. Letrozole inhibits the aromatase enzyme by competitively binding to the heme of the cytochrome P450 subunit of the enzyme, resulting in a reduction of estrogen biosynthesis in all tissues.

Caution

Please find SDS provided by EDQM here..

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

Unit quantity: 80 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

application(s)pharmaceutical (small molecule)
formatneat
Gene Informationhuman ... CYP19A1(1588)
gradepharmaceutical primary standard
InChI keyHPJKCIUCZWXJDR-UHFFFAOYSA-N
InChI1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
manufacturer/tradenameEDQM
SMILES stringN#CC(C=C1)=CC=C1C(N2C=NC=N2)C3=CC=C(C#N)C=C3
storage temp.2-8°C
Cas Number112809-51-5
This product has met the following criteria to qualify for the following awards:



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