UCN-01, >=97% (HPLC), powder

Code: U6508-1MG D2-231

Application

UCN-01 has been used to study checkpoint kinase-1 (CHK1) protein function in trophoblast stem (TS) cells. It has also been used to study UV-induced CHK1 phosphory...


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€227.74 1MG
€280.12 inc. VAT
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Application

UCN-01 has been used to study checkpoint kinase-1 (CHK1) protein function in trophoblast stem (TS) cells. It has also been used to study UV-induced CHK1 phosphorylation in IB10 cells.

Biochem/physiol Actions

UCN-01 is a selective inhibitor for conventional PKC isotypes over novel PKC isotypes.

Features and Benefits

This compound is featured on the PKB/Akt and PKC pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

1, 5 mg in glass bottle

Preparation Note

UCN-01 is soluble in DMSO at a concentration that is greater than 5 mg/ml. However, it is insoluble in water.

assay≥97% (HPLC)
colorlight yellow
formpowder
Gene Informationhuman ... CDK2(1017), CDK4(1019), CDK6(1021), CHEK1(1111), PDPK1(5170), PRKCA(5578), PRKCB(5579), PRKCD(5580), PRKCE(5581), PRKCG(5582), PRKCH(5583), PRKCI(5584), PRKCQ(5588), PRKCZ(5590), PRKD1(5587), PRKD3(23683)
optical activity[α]20/D 130 to 160°, c = 0.2 in DMSO
Quality Level100
SMILES string[H][C@@]1(C[C@@H](NC)[C@H]2OC)N3C4=C(N([C@@]2(C)O1)C5=C6C=CC=C5)C6=C7C(C(N[C@@H]7O)=O)=C4C8=C3C=CC=C8
solubilityDMSO: >5 mg/mL, H2O: insoluble
storage conditionprotect from light
storage temp.2-8°C
Cas Number112953-11-4
This product has met the following criteria to qualify for the following awards:



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