NOLATREXED DIHYDROCHLORIDE

Code: SML2909-25MG D2-231

Biochem/physiol Actions

Nolatrexed dihydrochloride is a water-soluble lipophilic quinazoline folate analog that exhibits potent antineoplastic activity. Nolatrexed is a poten...


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Biochem/physiol Actions

Nolatrexed dihydrochloride is a water-soluble lipophilic quinazoline folate analog that exhibits potent antineoplastic activity. Nolatrexed is a potent thymidylate synthase inhibitor that inhibits thymine synthesis followed by inhibition of DNA replication.

assay≥98% (HPLC)
colorwhite to beige
formpowder
Quality Level100
SMILES stringNC1=NC(C2=C(N1)C=CC(C)=C2SC3=CC=NC=C3)=O
solubilityH2O: 2 mg/mL, clear
storage conditiondesiccated
storage temp.2-8°C
Cas Number152946-68-4
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