SBI-797812

Code: SML2791-25MG D2-231

Biochem/physiol Actions

SBI-797812 is a cell penetrant and potent activator of nicotinamide phosphoribosyltransferase (NAMPT) that increases intracellular levels of NMN and N...


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Biochem/physiol Actions

SBI-797812 is a cell penetrant and potent activator of nicotinamide phosphoribosyltransferase (NAMPT) that increases intracellular levels of NMN and NAD+ in cells. SBI-797812 blocks binding of inhibitors to NAMPT and shifts the reaction equilibrium towards NMN formation. It elevates levels of NAD+ in mice liver.

assay≥98% (HPLC)
colorwhite to beige
formpowder
Quality Level100
SMILES stringO=C(NC1=CC=C(S(=O)(N(C2)C[C@H]3O[C@@H]2CC3)=O)C=C1)NCC4=CC=NC=C4
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
Cas Number2237268-08-3
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