RG1534

Code: SML2762-5MG D2-231

Biochem/physiol Actions

RG1534 is an inhibitor of hTERT promoter activity that selectively targets G-hairpin stem loop of the human telomerase reverse transcriptase gene (hTE...


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Biochem/physiol Actions

RG1534 is an inhibitor of hTERT promoter activity that selectively targets G-hairpin stem loop of the human telomerase reverse transcriptase gene (hTERT) that downregulates hTERT expression. RG1534 induces mitochondrial defects, oxidative stress, DNA damage and apoptosis in cancer cell while sparing normal cells

assay≥98% (HPLC)
colorwhite to beige
formpowder
Quality Level100
SMILES stringNC1=CC=CC=C1C(NC(NC2=CC(C)=C(C=C2)OC3=NC=C(C=N3)Cl)=O)=O
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
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