Biochem/physiol Actions
SRS11-92 is a cell penetrant and potent inhibitor of ferroptosis that attenuates the cell death associated with frataxin knockdown in healthy human fibroblasts. SRS11-92 protects against cell death in in a brain slice model of Huntington’;s disease, an oligodendrocyte model of periventricular leukomalacia, and in isolated kidney proximal tubules model of kidney disfunction.
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