CUET

Code: SML2675-100MG D2-231

Biochem/physiol Actions

CuET, a metabolite of disulfiram, is an inhibitor of p97 segregase adaptor NPL4 that exhibits potent anti-cancer effects. Apparently CuET binds NPL4 a...


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Biochem/physiol Actions

CuET, a metabolite of disulfiram, is an inhibitor of p97 segregase adaptor NPL4 that exhibits potent anti-cancer effects. Apparently CuET binds NPL4 and induces its aggregation, which disables the vital p97–NPL4–UFD1 pathway and induces to cell death.

assay≥97% (HPLC)
colordark green to black
formpowder
SMILES stringCCN(CC)C(S[Cu]SC(N(CC)CC)=S)=S
solubilityDMSO: 2 mg/mL, clear
storage conditiondesiccated
storage temp.2-8°C
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