SB4

Code: SML2636-25MG D2-231

Biochem/physiol Actions

Sb4 is a cell penetrant, potent bone morphogenetic protein (BMP) signaling agonist that rapidly activate BMP in human renal cells (HEK293). Sb4 activa...


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Biochem/physiol Actions

Sb4 is a cell penetrant, potent bone morphogenetic protein (BMP) signaling agonist that rapidly activate BMP in human renal cells (HEK293). Sb4 activates BMP by stabilization of intracellular p-SMAD-1/5/9. Apparently activation of the BMP pathway by sb4 cannot be reversed by inhibition of Noggin or type I BMP kinase inhibitors

assay≥98% (HPLC)
colorwhite to beige
formpowder
SMILES stringBrC1=CC=C(CSC2=NC3=C(C=CC=C3)O2)C=C1
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
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