IXABEPILONE

Code: SML2615-5MG D2-231

Biochem/physiol Actions

Ixabepilone is a microtubule stabilizing semisynthetic lactam analog of epothilone B. It appears that Ixabepilone is unaffected by BCRP mediated chemo...


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Biochem/physiol Actions

Ixabepilone is a microtubule stabilizing semisynthetic lactam analog of epothilone B. It appears that Ixabepilone is unaffected by BCRP mediated chemoresistance.

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyFABUFPQFXZVHFB-PVYNADRNSA-N
InChI1S/C27H42N2O5S/c1-15-9-8-10-27(7)22(34-27)12-20(16(2)11-19-14-35-18(4)28-19)29-23(31)13-21(30)26(5,6)25(33)17(3)24(15)32/h11,14-15,17,20-22,24,30,32H,8-10,12-13H2,1-7H3,(H,29,31)/b16-11+/t15-,17+,20-,21-,22-,24-,27+/m0/s1
optical activity[α]/D -35 to -45°, c = 1.0 in chloroform-d
solubilityDMSO: 2 mg/mL, clear
storage conditionprotect from light
storage temp.−20°C
Cas Number219989-84-1
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