OB-1

Code: SML2560-25MG D2-231

Biochem/physiol Actions

OB-1 is an inhibitor of the oligomerization of Stomatin-like protein-3 (STOML3), which is a modulator of the mechanosensitive ion channel Piezo2. STOM...


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€246.38 25MG
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Biochem/physiol Actions

OB-1 is an inhibitor of the oligomerization of Stomatin-like protein-3 (STOML3), which is a modulator of the mechanosensitive ion channel Piezo2. STOML3 requires oligomerization for its role as an endogenous regulator of the sensitivity of mechanosensitive Piezo ion channels in sensory neurons. By inhibiting this activity, OB-1 has been shown to reduce touch-evoked pain behavior in two mouse models of neuropathic pain.

assay≥98% (HPLC)
colorwhite to very dark brown
formpowder
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
Cas Number300803-69-4
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