PT-TTPY

Code: SML2556-25MG D2-231

Biochem/physiol Actions

Pt-ttpy, a metallo-organic complex, is a G-quadruplex ligand that potently induces significant telomere-associated DNA damage in cancer cells. It inhi...


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€362.40 25MG
€445.75 inc. VAT
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Biochem/physiol Actions

Pt-ttpy, a metallo-organic complex, is a G-quadruplex ligand that potently induces significant telomere-associated DNA damage in cancer cells. It inhibits telomerase and/or telomere functions. Pt-ttpy induces number of chromatin defects in mitosis including chromatin bridges, ultrafine bridges (UFBs), and double-stranded breaks (DSBs).

assay>97% (NMR)
colorfaint yellow to dark orange
formpowder
SMILES stringCC1=CC=C(C2=CC(C3=[N+]4C=CC=C3)=[N+]5C(C6=CC=CC=[N+]6[Pt-2]54Cl)=C2)C=C1.[Cl-]
solubilityDMSO: 0.2 mg/mL (warmed)
storage temp.2-8°C
Cas Number727721-37-1
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