AP-C5

Code: SML2552-5MG D2-231

Biochem/physiol Actions

AP-C5 is a potent and selective inhibitor of the guanosine 3’;,5’;-cyclicmonophosphate (cGMP)-dependent protein kinase II (cGKII)that se...


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Biochem/physiol Actions

AP-C5 is a potent and selective inhibitor of the guanosine 3’;,5’;-cyclicmonophosphate (cGMP)-dependent protein kinase II (cGKII)that selectively blocks cGKII dependent phosphorylation of the vasodilator-stimulated phosphoprotein (VASP) in intestinal organoids. AP-C5 mitigates secretory response provoked by the GCC-activating Escherichia coli heat-stable toxin (STa) in mouse small intestinal tissue.

assay≥98% (HPLC)
colorwhite to beige
formpowder
Quality Level100
SMILES stringC#CCNC1=NC=CC(C2=CC=C(N3C=NC=C3)C=C2)=N1
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
Cas Number2234272-10-5
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