OXANTHROQUINONE G01

Code: SML2469-5MG D2-231

Biochem/physiol Actions

Oxanthroquinone G01 is a potent inhibitor of KRAS and NRAS plasma membrane localization that potently inhibits proliferation of KRAS transformed cance...


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€89.90 5MG
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Biochem/physiol Actions

Oxanthroquinone G01 is a potent inhibitor of KRAS and NRAS plasma membrane localization that potently inhibits proliferation of KRAS transformed cancer cells. Oxanthroquinone G01 also inhibits recycling of epidermal growth factor receptor and transferrin receptor, but has no influence on cholera toxin internalization. It also increases cellular levels of sphingomyelin and and ceramide.

assay≥98% (HPLC)
colorfaint yellow to dark orange
formpowder
SMILES stringO=C1C2=C(C=C(OC)C(C(OCC)=O)=C2C)C(C3=CC=C(C)C(O)=C31)=O
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
Cas Number1616622-15-1
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