CY-09

Code: SML2465-5MG D2-231

Biochem/physiol Actions

CY-09 is an NLRP3 inflammasone inhibitor. CY-09 binds directly to the ATP-binding motif of NLRP3 NACHT domain and inhibits its ATPase activity, blocki...


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€93.20 5MG
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Biochem/physiol Actions

CY-09 is an NLRP3 inflammasone inhibitor. CY-09 binds directly to the ATP-binding motif of NLRP3 NACHT domain and inhibits its ATPase activity, blocking NLRP3 inflammasome assembly and activation. In mouse models CY-09 showed therapeutic effects in type 2 diabetes and cryopyrin-associated auto-inflammatory syndrome (CAPS), which is caused by gain-of-function mutations of NLRP3.

assay≥98% (HPLC)
colorfaint yellow to dark orange
formpowder
SMILES stringOC(C(C=C1)=CC=C1/C=C(SC2=S)C(N2CC3=CC=CC(C(F)(F)F)=C3)=O)=O
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
Cas Number1073612-91-5
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