JNS 1-40

Code: SML2390-25MG D2-231

Biochem/physiol Actions

JNS 1-40 is a potent and selective cysteine-reactive covalent ligand of regulatory subunit PPP2R1A of the tumor-suppressor protein phosphatase 2A (PP2...


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€324.41 25MG
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Biochem/physiol Actions

JNS 1-40 is a potent and selective cysteine-reactive covalent ligand of regulatory subunit PPP2R1A of the tumor-suppressor protein phosphatase 2A (PP2A) that activate PP2A in vitro and in vivo. JNS 1-40 targets C377 of PPP2R1A and inhibits breast cancer proliferation, and in vivo tumor growth.

assay≥95% (HPLC)
colorwhite to beige
formpowder
SMILES stringO=C(CCl)N(CC1=CC=CC=C1)C2=CC3=C(OCCO3)C=C2
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
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