BAY-707

Code: SML2348-5MG D2-231

Biochem/physiol Actions

BAY-707 is an inhibitor of the human 7,8-dihydro-8-oxoguaninetriphosphatase MTH1 (NUDT1), which hydrolyzes oxidized purine nucleoside triphosphates th...


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€94.20 5MG
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Biochem/physiol Actions

BAY-707 is an inhibitor of the human 7,8-dihydro-8-oxoguaninetriphosphatase MTH1 (NUDT1), which hydrolyzes oxidized purine nucleoside triphosphates that might otherwise be incorporated into DNA/RNA and contribute to DNA damage. BAY-707 was shown to be a substrate-competitive, selective MTH1 inhibitor with an IC50 value of 2.3 nM.

assay≥98% (HPLC)
colorwhite to beige
formpowder
SMILES stringO=C(NCC)C1=CC2=C(N1)N=CC=C2N3CCOC[C@@H]3C
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
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