Biochem/physiol Actions
Celgosivir is a prodrug of natural bicyclic iminosugar castanospermine that exhibits antiviral activity in vivo including HCV and dengue. Celgosivir is an inhibitor of α-glucosidases, which inhibits glycoprotein processing in cell culture. Apparently inhibition of α-glucosidases within infected cell prevents secretion of virus.
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