LENALIDOMIDE

Code: SML2283-250MG D2-231

Biochem/physiol Actions

Lenalidomide, a derivative of thalidomide, is an immunomodulatory agent that is approved drug for treatment of multiple myeloma. Apparently Lenalidomi...


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Biochem/physiol Actions

Lenalidomide, a derivative of thalidomide, is an immunomodulatory agent that is approved drug for treatment of multiple myeloma. Apparently Lenalidomide is a ligand of ubiquitin E3 ligase cereblon that induces the enzyme to degrade the Ikaros transcription factors IKAROS family zinc finger 1 (IKZF1) and IKZF3. Lenalidomide possess pleiotropic antitumor effects. It is used in the treatment of 5q-deletion associated myelodysplastic syndrome (del(5q)-MDS).

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyGOTYRUGSSMKFNF-UHFFFAOYSA-N
InChI1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
SMILES stringO=C1N(C2CCC(NC2=O)=O)CC3=C1C=CC=C3N
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
Cas Number191732-72-6
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