COL003

Code: SML2264-5MG D2-231

Biochem/physiol Actions

Col003 is a cell penetrant, selective and potent inhibitor of the interaction of Hsp47 with collagen. It binds to the collagen binding site on Hsp47. ...


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€112.90 5MG
€138.87 inc. VAT
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Biochem/physiol Actions

Col003 is a cell penetrant, selective and potent inhibitor of the interaction of Hsp47 with collagen. It binds to the collagen binding site on Hsp47. Col003 inhibits a collagen secretion by destabilization the collagen triple helix. Additionally Col003 weakly inhibits interaction of collagen with prolyl 4-hydroxylase (P4H).

assay≥98% (HPLC)
coloryellow to orange
formpowder
SMILES stringOC1=C(C=C(C=C1C=O)CC2=CC=CC=C2)[N+]([O-])=O
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
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