D3-(b)ARR

Code: SML2256-5MG D2-231

Biochem/physiol Actions

D3-βArr is a positive allosteric modulator of TSHR (thyrotropin receptor) for β-Arr 1-mediated signaling that initiates translocation of ...


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Biochem/physiol Actions

D3-βArr is a positive allosteric modulator of TSHR (thyrotropin receptor) for β-Arr 1-mediated signaling that initiates translocation of β-Arr 1 by direct TSHR activation, while showing no agonistic effect on cAMP production. D3-βarr is a positive allosteric modulator for TSH-enhanced osteoblast differentiation.

assay≥98% (HPLC)
colorwhite to beige
formpowder
SMILES stringCC(C1=CC=CC=C1)NC2=NC(N3CCNCC3)=NC4=CC=CC=C42
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
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