J-113397

Code: SML2254-5MG D2-231

Biochem/physiol Actions

J-113397 is an antagonist of NOP, the nociceptin/orphanin FQ (N/OFQ) receptor. J-113397 exhibited an IC50 value of 2.3 nM in Chinese hamster ovary (CH...


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€153.21 5MG
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Biochem/physiol Actions

J-113397 is an antagonist of NOP, the nociceptin/orphanin FQ (N/OFQ) receptor. J-113397 exhibited an IC50 value of 2.3 nM in Chinese hamster ovary (CHO) cells expressing ORL1 receptor showed with 600-fold or less affinity for µ-, δ- and κ-opioid receptors.

assay≥98% (HPLC)
colorwhite to beige
formpowder
optical activity[α]/D +7 to +10°, c = 1 in isopropanol
SMILES stringCCN1C2=CC=CC=C2N([C@H]3[C@H](CO)CN(CC4CCCCCCC4)CC3)C1=O
solubilityDMSO: 2 mg/mL, clear
storage conditiondesiccated
storage temp.room temp
Cas Number256640-45-6
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