CL075

Code: SML2235-25MG D2-231

Application

CL075 has been used to activate the monocyte-derived dendritic cells (DCs) to demonstrate the ability of DCs to induce cell death.

Biochem/physiol A...


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€454.50 25MG
€559.04 inc. VAT
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Application

CL075 has been used to activate the monocyte-derived dendritic cells (DCs) to demonstrate the ability of DCs to induce cell death.

Biochem/physiol Actions

CL075 is a thiazoloquinolone derivative. It might influence tumor development.

CL075 is a selective agonist of Toll-like receptor-8 (TLR-8) with immunostimulant activity. It showed an EC50 value of 400nM for IRF-NFκB stimulation in TLR8 compared to 4 µM for TLR7.

assay≥98% (HPLC)
colorwhite to beige
formpowder
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
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