1S;3R-RSL 3

Code: SML2234-5MG D2-231

Application

1S,3R-RSL 3 has been used:as a glutathione peroxidase 4 (GPX4) inhibitor to study its effects on cell death in subventricular glioblastoma multiforme (GBM) linesG...


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€104.55 5MG
€128.60 inc. VAT
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Application

1S,3R-RSL 3 has been used:as a glutathione peroxidase 4 (GPX4) inhibitor to study its effects on cell death in subventricular glioblastoma multiforme (GBM) linesGPX4 inhibitor and ferroptosis inducer to study its effects on cardiomyocyte death and heart failure in miceas a ferroptosis inducer in HT-1080 cellsin cell viability assay

Biochem/physiol Actions

RSL3 is an inducer of ferroptosis. It acts by a different method than erastin to induce ferroptosis by inhibiting glutathione peroxidase 4 (GPX4).

assay≥98% (HPLC)
colorwhite to beige
formpowder
solubilityDMSO: 2 mg/mL, clear
storage temp.−20°C
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