RL5A

Code: SML2187-25MG D2-231

Biochem/physiol Actions

RL5a is a potent inhibitor of the replication licensing system in human cells. RL5a blocks the binding of the origin recognition complex (ORC) to orig...


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€309.52 25MG
€380.71 inc. VAT

Biochem/physiol Actions

RL5a is a potent inhibitor of the replication licensing system in human cells. RL5a blocks the binding of the origin recognition complex (ORC) to origin DNA, which is required interaction for licensing. RL5a appears to act as noncompetitive inhibitor of ORC with respect to ATP.

assay≥98% (HPLC)
colorwhite to very dark brown
formpowder
InChI keyCRGKLHXVNVZAPA-UHFFFAOYSA-N
InChI1S/C17H19N3O/c1-20(2)10-9-18-15-12-16(17-8-5-11-21-17)19-14-7-4-3-6-13(14)15/h3-8,11-12H,9-10H2,1-2H3,(H,18,19)
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
Cas Number133671-66-6
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