KEA1-97

Code: SML2180-5MG D2-231

Biochem/physiol Actions

KEA1-97 is a Thioredoxin-Caspase 3 interaction disruptor. It was found to target lysine 72 of thioredoxin, inhibiting its interactions with caspase 3 ...


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€63.35 5MG
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Biochem/physiol Actions

KEA1-97 is a Thioredoxin-Caspase 3 interaction disruptor. It was found to target lysine 72 of thioredoxin, inhibiting its interactions with caspase 3 and inducing apoptosis without affecting other thioredoxin activity. KEA1-97 induced apoptosis in breast cancer cells and treatment of immune-deficient SCID mice at 5 mg/kg ip impaired breast tumor xenograft growth.

assay≥98% (HPLC)
colorwhite to beige
formpowder
SMILES stringFC1=CC=C(C2=CC=C(NC3=NC(Cl)=NC(Cl)=N3)C=C2)C=C1
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
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