SR-18292 MALEATE

Code: SML2146-25MG D2-231

Application

SR-18292 Maleate has been used as a peroxisome proliferator-activated receptor γ coactivator 1 α (PGC1α) inhibitor to study the protective effects of pioglitazone...


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€409.00 25MG
€503.07 inc. VAT
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Application

SR-18292 Maleate has been used as a peroxisome proliferator-activated receptor γ coactivator 1 α (PGC1α) inhibitor to study the protective effects of pioglitazone on demyelinated axons.

Biochem/physiol Actions

SR-18292 is a potent and specific inhibitor of hepatic gluconeogenesis via increased acetylation of PGC-1α and suppression of gluconeogenic gene expression. SR-18292 reduces blood glucose and increases hepatic insulin sensitivity in mouse models of T2D.

assay≥98% (HPLC)
colorwhite to beige
formpowder
SMILES stringCC(C)(C)N(CC(O)COC1=CC=CC2=C1C=CN2)CC3=CC=C(C)C=C3.O=C(O)/C=CC(O)=O
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
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