HA15

Code: SML2118-5MG D2-231

Biochem/physiol Actions

HA15 is a selective ligand of BiP/GRP78/HSPA5 chaperone that increases ER stress, leading to autophagic and apoptotic cell death in varies cancer cell...


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€112.90 5MG
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Biochem/physiol Actions

HA15 is a selective ligand of BiP/GRP78/HSPA5 chaperone that increases ER stress, leading to autophagic and apoptotic cell death in varies cancer cell lines including melanoma cells. HA15 inhibits inhibit the ATPase activity of BiP. HA15 inhibits tumor development in mice injected with A375 melanoma cells.

assay≥98% (HPLC)
colorwhite to beige
formpowder
SMILES stringCC(NC1=NC(C2=CC=CC(NS(C3=C(C=CC=C4N(C)C)C4=CC=C3)(=O)=O)=C2)=CS1)=O
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
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