DROTAVERINE HYDROCHLORIDE

Code: SML1942-10MG D2-231

Biochem/physiol Actions

Drotaverine (Drotaverin) is an isoquinoline-based PDE4-selective phosphodiesterase (PDE) inhibitor and an L-type voltage-dependent (voltage-operated) ...


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Biochem/physiol Actions

Drotaverine (Drotaverin) is an isoquinoline-based PDE4-selective phosphodiesterase (PDE) inhibitor and an L-type voltage-dependent (voltage-operated) calcium channel (L-VDCC or L-VOCC) blocker that exhibits in vivo antispasmodic efficacy without anticholinergic effects.

It is a benzylisoquinoline derivative. Drotaverine acts as a smooth muscle relaxant.

assay≥95% (HPLC)
colorwhite to beige
formpowder
InChI keyJBFLYOLJRKJYNV-MASIZSFYSA-N
InChI1S/C24H31NO4.ClH/c1-5-26-21-10-9-17(14-22(21)27-6-2)13-20-19-16-24(29-8-4)23(28-7-3)15-18(19)11-12-25-20;/h9-10,13-16,25H,5-8,11-12H2,1-4H3;1H/b20-13-;
Quality Level100
SMILES stringCCOC1=CC=C(/C=C2C3=C(CCN/2)C=C(OCC)C(OCC)=C3)C=C1OCC.[H]Cl
solubilityDMSO: 2 mg/mL, clear (warmed)
storage conditiondesiccated
storage temp.2-8°C
Cas Number985-12-6
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