IGURATIMOD

Code: SML1898-25MG D2-231

Biochem/physiol Actions

Iguratimod (T-614) is an orally active anti-inflammatory compound that inhibits NF-kappaB (NF-KB) p65 subunit (RelA) phosphorylation and nuclear trans...


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€411.00 25MG
€505.53 inc. VAT
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Biochem/physiol Actions

Iguratimod (T-614) is an orally active anti-inflammatory compound that inhibits NF-kappaB (NF-KB) p65 subunit (RelA) phosphorylation and nuclear translocation (30 µg/mL against 10 ng/mL TNF-α; human synovial cells) without affecting IKBα degradation.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyANMATWQYLIFGOK-UHFFFAOYSA-N
InChI1S/C17H14N2O6S/c1-26(22,23)19-13-8-15-12(17(21)14(9-24-15)18-10-20)7-16(13)25-11-5-3-2-4-6-11/h2-10,19H,1H3,(H,18,20)
Quality Level100
SMILES stringO=S(NC1=CC(OC=C(NC([H])=O)C2=O)=C2C=C1OC3=CC=CC=C3)(C)=O
solubilityDMSO: 5 mg/mL, clear (warmed)
storage temp.2-8°C
Cas Number123663-49-0
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