KYA1797K POTASSIUM SALT

Code: SML1831-5MG D2-231

Biochem/physiol Actions

KYA1797K is an inhibitor of both Wnt/β-catenin and Ras pathways. It binds to the axin regulators of the G-protein signaling (RGS) domain enhancin...


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Your Price
€150.18 5MG
Discontinued
€184.72 inc. VAT

Biochem/physiol Actions

KYA1797K is an inhibitor of both Wnt/β-catenin and Ras pathways. It binds to the axin regulators of the G-protein signaling (RGS) domain enhancing formation of the β-catenin destruction complex and inducing activation GSK3β, which results in phosphorylation and subsequent degradation of both β-catenin and K-Ras. KYA1797K was show to suppress tumor growth and progression in mouse xenografts of CRC cells that had APC and K-Ras mutations.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colororange to dark red
formpowder
Quality Level100
SMILES string[O-]C(CCN1C(/C(SC1=S)=C/C2=CC=C(C3=CC=C([N+]([O-])=O)C=C3)O2)=O)=O.[K+]
solubilityDMSO: 2 mg/mL, clear (warmed)
storage temp.2-8°C
Cas Number1956356-56-1
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