LESINURAD

Code: SML1607-10MG D2-231

Biochem/physiol Actions

Lesinurad is a selective inhibitor of Urate transporter 1 (URAT1), a urate-anion exchanger which is responsible for the majority of uric acid reabsorp...


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€107.66 10MG
€132.42 inc. VAT
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Biochem/physiol Actions

Lesinurad is a selective inhibitor of Urate transporter 1 (URAT1), a urate-anion exchanger which is responsible for the majority of uric acid reabsorption from the renal tubular lumen. Lesinurad thus reduces serum uric acid levels. Lesinurad has been approved for use in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout.

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
Gene Informationhuman ... SLC22A12(116085)
InChI keyFGQFOYHRJSUHMR-UHFFFAOYSA-N
InChI1S/C17H14BrN3O2S/c18-16-19-20-17(24-9-15(22)23)21(16)14-8-7-11(10-5-6-10)12-3-1-2-4-13(12)14/h1-4,7-8,10H,5-6,9H2,(H,22,23)
Quality Level100
SMILES stringBrC1=NN=C(SCC(O)=O)N1C2=C3C(C=CC=C3)=C(C4CC4)C=C2
solubilityDMSO: 25 mg/mL, clear
storage temp.−20°C
Cas Number878672-00-5
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