TIPIRACIL HYDROCHLORIDE

Code: SML1552-50MG D2-231

Biochem/physiol Actions

Tipiracil is an inhibitor of thymidine phosphorylase. Tipiracil is used in combination with trifluridine as TAS-102 for the treatment of refractory me...


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€718.43 50MG
€883.67 inc. VAT
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Biochem/physiol Actions

Tipiracil is an inhibitor of thymidine phosphorylase. Tipiracil is used in combination with trifluridine as TAS-102 for the treatment of refractory metastatic colorectal cancer. Tipiracil increases the bioavailability of trifluridine by blocking the enzyme that would otherwise protect the tumors by metabolizing trifluridine.

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
Gene Informationhuman ... TYMP(1890)
InChI keyKGHYQYACJRXCAT-UHFFFAOYSA-N
InChI1S/C9H11ClN4O2.ClH/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11;/h11H,1-4H2,(H2,12,13,15,16);1H
Quality Level100
SMILES string[H]Cl.ClC1=C(CN2C(CCC2)=N)NC(NC1=O)=O
solubilityH2O: 5 mg/mL, clear (warmed)
storage conditiondesiccated
storage temp.2-8°C
Cas Number183204-72-0
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