MK6-83

Code: SML1509-25MG D2-231

Biochem/physiol Actions

MK6-83 is a potent activator of wild type and mutant variants F465L and F408D of TRPML1 channel. MK6-83 weakly activates TRPML mutants R403C or V446L....


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€444.10 25MG
€546.24 inc. VAT
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Biochem/physiol Actions

MK6-83 is a potent activator of wild type and mutant variants F465L and F408D of TRPML1 channel. MK6-83 weakly activates TRPML mutants R403C or V446L. MK6-83 restores channel function and rescue disease associated abnormalities in mucolipidosis type IV (MLIV) patient cells.

MK6-83is known to stimulate caspase-3-dependent apoptosis. It can also decrease the viability of cells.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to brown
formpowder
Quality Level100
solubilityDMSO: 5 mg/mL, clear (warmed)
storage temp.2-8°C
Cas Number1062271-24-2
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