Application
Tegaserod maleate has been used to study its cytotoxic effects on human astrocytes and to study its effects as an anti-glioblastoma agent.
Biochem/physiol Actions
It stimulates neurotransmitter release from enteric nerves and regularizes gastrointestinal function. Tegaserod has been used to treat irritable bowel syndrome associated with constipation and chronic constipation.
Tegaserod is a potent full agonist at serotonin 5-HT4 receptors with an EC50 of 7 nM.
Packaging
10, 50 mg in glass bottle
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