FICZ

Code: SML1489-1MG D2-231

Biochem/physiol Actions

FICZ (6-formylindolo(3,2b)carbazole) being a photooxidation product of tryptophan, might serve as a chemical messenger of light.

FICZ is a poten...


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Your Price
€164.60 1MG
€202.46 inc. VAT

Biochem/physiol Actions

FICZ (6-formylindolo(3,2b)carbazole) being a photooxidation product of tryptophan, might serve as a chemical messenger of light.

FICZ is a potent high affinity ligand of the aryl hydrocarbon receptor (AhR), which is a ligand-activated transcription factor that activates the expression of aromatic hydrocarbon metabolizing enzyme genes such as the CYP1A1 gene and has also been shown to have multiple additional roles in cell-cycle regulation, development and maturation of many tissues, control of inflammation, and immune response. FICZ is a photoproduct of tryptophan and is believed to be an endogenous AhR ligand. It is extremely potent, with a Kd value of 0.07 nM.

Packaging

1, 5 mg in glass bottle

assay≥95% (HPLC)
coloryellow
formlyophilized powder
Quality Level100
solubilityDMSO: 0.5 mg/mL, clear (warmed)
storage temp.−20°C
Cas Number172922-91-7
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