IBUFENAC

Code: SML1452-50MG D2-231

Biochem/physiol Actions

Ibufenac is a non-steroidal anti-inflammatory drug (NSAID) analog of ibuprofen that was withdrawn for hepatotoxicity. It inhibits cyclooxygenases COX-...


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€170.81 50MG
€210.10 inc. VAT
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Biochem/physiol Actions

Ibufenac is a non-steroidal anti-inflammatory drug (NSAID) analog of ibuprofen that was withdrawn for hepatotoxicity. It inhibits cyclooxygenases COX-1 and -2 activity with IC50 values of 17.4 and 13.1 µM, respectively and > 40 µM for 5-LOX. It has been used in studies of drug-induced hepatotoxicity.

Packaging

10, 50 mg in glass bottle

assay≥95% (HPLC)
colorwhite to beige
formpowder
Gene Informationhuman ... PTGS1(5742), PTGS2(5743)
InChI keyCYWFCPPBTWOZSF-UHFFFAOYSA-N
InChI1S/C12H16O2/c1-9(2)7-10-3-5-11(6-4-10)8-12(13)14/h3-6,9H,7-8H2,1-2H3,(H,13,14)
Quality Level100
SMILES stringOC(CC1=CC=C(CC(C)C)C=C1)=O
solubilityDMSO: 20 mg/mL, clear
storage temp.−20°C
Cas Number1553-60-2
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