STF-118804

Code: SML1348-5MG D2-231

Biochem/physiol Actions

STF-118804 is a highly specific and potent NAMPT (nicotinamide phosphoribosyl transferase) inhibitor that reduces the viability of most B-ALL cell lin...


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€136.70 5MG
€168.14 inc. VAT
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Biochem/physiol Actions

STF-118804 is a highly specific and potent NAMPT (nicotinamide phosphoribosyl transferase) inhibitor that reduces the viability of most B-ALL cell lines. STF 118804 induces leukemia cell apoptosis including leukemia initiating (stem) cells. STF 118804 improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia.

STF-118804 displays pancreatic ductal adenocarcinoma (PDAC) growth reducing potential in combination with chemotherapeutic drugs.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyDLFCEZOMHBPDGI-UHFFFAOYSA-N
InChI1S/C25H23N3O4S/c1-17-5-11-22(12-6-17)33(30,31)16-23-18(2)32-25(28-23)21-9-7-20(8-10-21)24(29)27-15-19-4-3-13-26-14-19/h3-14H,15-16H2,1-2H3,(H,27,29)
Quality Level100
SMILES stringO=C(C1=CC=C(C2=NC(CS(=O)(C3=CC=C(C)C=C3)=O)=C(C)O2)C=C1)NCC4=CN=CC=C4
solubilityDMSO: 20 mg/mL, clear
storage temp.2-8°C
Cas Number894187-61-2
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