TWS119

Code: SML1271-25MG D2-231

Application

TWS119 has been used as glycogen synthase kinase-3β (GSK-3β) GSK3β inhibitor.

Biochem/physiol Actions

TWS119 favors the γδT cells sur...


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€461.70 25MG
€567.89 inc. VAT
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Application

TWS119 has been used as glycogen synthase kinase-3β (GSK-3β) GSK3β inhibitor.

Biochem/physiol Actions

TWS119 favors the γδT cells survival and proliferation by activating the mammalian target of rapamycin (mTOR) pathway. It also promotes the expression of T-cell factor 1 (TCF1) and modulates cytokine production.

TWS119 is a potent Glycogen synthase kinase-3β (GSK-3β) inhibitor that can induce neurogenesis in embryonic stem cells (ESCs).

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyVPVLEBIVXZSOMQ-UHFFFAOYSA-N
InChI1S/C18H14N4O2/c19-12-4-1-3-11(7-12)16-9-15-17(22-16)20-10-21-18(15)24-14-6-2-5-13(23)8-14/h1-10,23H,19H2,(H,20,21,22)
Quality Level100
SMILES stringOC1=CC(OC2=NC=NC3=C2C=C(C4=CC=CC(N)=C4)N3)=CC=C1
solubilityDMSO: 20 mg/mL, clear
storage temp.2-8°C
Cas Number601514-19-6
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