(2S)-Hypusine dihydrochloride

Code: SML1158-5MG D2-231

Biochem/physiol Actions

(2S)-Hypusine is an unusual amino acid found only in eukaryotic translation initiation factor 5A (eIF5A) and a similar protein in archaebacteria. (2S)...


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€200.61 5MG
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Biochem/physiol Actions

(2S)-Hypusine is an unusual amino acid found only in eukaryotic translation initiation factor 5A (eIF5A) and a similar protein in archaebacteria. (2S)-Hypusine is formed by posttranslational modification of a lysine with the addition of the 4-aminobutyl moiety from the polyamine spermidine. There is increasing interest in the polyamine-hypusine axis and eIF5A, its a role in cell growth and differentiation, and a recent paper on the polyamine-hypusine axis as a potential new tumour suppressor network.

Packaging

5, 25 mg in glass bottle

assay≥95% (HPLC)
colorwhite to beige
formpowder
InChI keyUTSZZUVUESAPQD-AHBBCRTASA-N
InChI1S/C10H23N3O3.2ClH/c11-5-4-8(14)7-13-6-2-1-3-9(12)10(15)16;;/h8-9,13-14H,1-7,11-12H2,(H,15,16);2*1H/t8?,9-;;/m0../s1
Quality Level100
SMILES string[H]Cl.[H]Cl.N[C@H](C(O)=O)CCCCNCC(O)CCN
solubilityH2O: 15 mg/mL, clear
storage conditiondesiccated
storage temp.−20°C
Cas Number82310-93-8
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