ROSTAFUROXIN

Code: SML1139-25MG D2-231

Biochem/physiol Actions

Rostafuroxin is a digitoxygenin derivative that selectively antagonizes the effects of endogenous ouabain on the Na+,K+-ATPase, ...


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€452.40 25MG
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Biochem/physiol Actions

Rostafuroxin is a digitoxygenin derivative that selectively antagonizes the effects of endogenous ouabain on the Na+,K+-ATPase, which maintains sodium and potassium ion gradients across plasma membranes. Rostafuroxin lowers blood pressure (BP) in animal models of hypertension.

Rostafuroxin is a derivative of digitoxigenin. It protects animal models against podocyte lesions and proteinuria by counteracting mutant β-adducin and ouabain-mediated effects.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyAEAPORIZZWBIEX-DTBDINHYSA-N
InChI1S/C23H34O4/c1-20-8-5-17(24)13-15(20)3-4-19-18(20)6-9-21(2)22(25,10-11-23(19,21)26)16-7-12-27-14-16/h7,12,14-15,17-19,24-26H,3-6,8-11,13H2,1-2H3/t15-,17+,18+,19-,20+,21-,22+,23+/m1/s1
Quality Level100
solubilityDMSO: 20 mg/mL, clear
storage temp.−20°C
Cas Number156722-18-8
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