IWP-4

Code: SML1114-5MG D2-231

Biochem/physiol Actions

IWP-4 is a potent inhbitor of the Wnt pathway regulatory protein porupine (Porcn). IWP-4 blocks palmitylation, and subsquent secretion and activity of...


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€250.60 5MG
€308.24 inc. VAT
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Biochem/physiol Actions

IWP-4 is a potent inhbitor of the Wnt pathway regulatory protein porupine (Porcn). IWP-4 blocks palmitylation, and subsquent secretion and activity of Wnt. IWP-4 induces the differentiation of human pluripotent stem cells into cardiomyocytes.

IWP-4 blocks Wnt family member 5a. It blocks Wnt protein secretion and prevents the canonical and non-canonical signaling pathways.

Packaging

5, 25 mg in glass bottle

assay≥95% (HPLC)
colorwhite to light brown
formpowder
InChI keyRHUJMHOIQBDFQR-UHFFFAOYSA-N
InChI1S/C23H20N4O3S3/c1-13-7-8-14-18(11-13)33-22(24-14)26-19(28)12-32-23-25-15-9-10-31-20(15)21(29)27(23)16-5-3-4-6-17(16)30-2/h3-8,11H,9-10,12H2,1-2H3,(H,24,26,28)
Quality Level100
SMILES stringO=C1C2=C(CCS2)N=C(SCC(NC3=NC(C=CC(C)=C4)=C4S3)=O)N1C5=C(OC)C=CC=C5
solubilityDMSO: 0.5 mg/mL, clear (warmed)
storage temp.−20°C
Cas Number686772-17-8
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