FEBRIFUGINE DIHYDROCHLORIDE >=95%

Code: SML0681-5MG D2-231

Biochem/physiol Actions

Febrifugine is an antimalarial, the active component of the Chinese herb Chang Shan. Recent studies indicate that its mechanism of action is as an inh...


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€157.35 5MG
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Biochem/physiol Actions

Febrifugine is an antimalarial, the active component of the Chinese herb Chang Shan. Recent studies indicate that its mechanism of action is as an inhibitor of prolyl-transfer RNA synthetase (ProRS).

Febrifugine dihydrochloride exhibits strong antimalarial activity against Plasmodium falciparum, the most insidious malaria causative agent. The adverse effects of febrifugine include diarrhoea, vomiting and liver toxicity.

Packaging

5, 25 mg in glass bottle

assay≥95% (HPLC)
coloroff-white to gray-brown
formpowder
InChI keySNTOTCUGCWLHEZ-KKJWGQAZSA-N
InChI1S/C17H20N2O3.CH4/c20-13(9-12-5-1-4-8-16(12)21)10-19-11-18-15-7-3-2-6-14(15)17(19)22;/h2-3,6-7,11-12,16,21H,1,4-5,8-10H2;1H4/t12-,16+;/m1./s1
optical activity[α]/D 10 to 15°, c = 1 in H2O
Quality Level100
SMILES stringO=C1C2=CC=CC=C2N=CN1CC(C[C@@H]3[C@@H](O)CCCC3)=O.C
solubilityH2O: 15 mg/mL, clear
storage conditiondesiccated
storage temp.−20°C
Cas Number32434-42-7
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