PR-619, >=95% (HPLC)

Code: SML0430-5MG D2-231

Application

PR-619 has been used:as a component of lysis buffer and also as a deubiquitinase inhibitor to treat proteins derived from SILAC-labeled Jurkat cellsas a pan-deubi...


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€318.90 5MG
€392.25 inc. VAT
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Application

PR-619 has been used:as a component of lysis buffer and also as a deubiquitinase inhibitor to treat proteins derived from SILAC-labeled Jurkat cellsas a pan-deubiquitinase inhibitor to study its effect on adenoassociated virus (AAV) transductionin radioimmunoprecipitation assay buffer (RIPA) buffer used for ubiquitination assays

Biochem/physiol Actions

PR-619 is a cell permeable broad spectrum deubiquitylating enzymes (DBUs) inhibitor. PR-619 induces the accumulation of polyubiquitylated proteins in cells without directly affecting proteasome activity.

Packaging

1, 5 mg in glass bottle

assay≥95% (HPLC)
colorwhite to beige
formpowder
InChI keyZXOBLNBVNROVLC-UHFFFAOYSA-N
InChI1S/C7H5N5S2/c8-2-13-4-1-5(14-3-9)7(11)12-6(4)10/h1H,(H4,10,11,12)
Quality Level100
SMILES stringNc1nc(N)c(SC#N)cc1SC#N
solubilityDMSO: 5 mg/mL (clear solution)
storage temp.−20°C
Cas Number2645-32-1
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