Nodinitib-1, >=98% (HPLC)

Code: SML0379-5MG D2-231

Biochem/physiol Actions

Nodinitib-1 (ML130) is a selectiove inhibitor of of the nucleotide oligomerization domain (NOD)-1 receptor, which is involved in innate immune respons...


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€135.70 5MG
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Biochem/physiol Actions

Nodinitib-1 (ML130) is a selectiove inhibitor of of the nucleotide oligomerization domain (NOD)-1 receptor, which is involved in innate immune response and has been associated with several inflammatory diseases. NOD1 and NOD2 recognize distinct structures derived from bacterial peptidoglycans and directly activate NF-?B pathway, which controls the production of proinflammatory molecules. Nodinitib-1 has 40:1 selectivity for NOD1 over NOD2.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keySRFABRWQVPCPRG-UHFFFAOYSA-N
InChI1S/C14H13N3O2S/c1-10-6-8-11(9-7-10)20(18,19)17-13-5-3-2-4-12(13)16-14(17)15/h2-9H,1H3,(H2,15,16)
Quality Level100
SMILES stringNC1=NC2=C(N1S(C3=CC=C(C)C=C3)(=O)=O)C=CC=C2
solubilityDMSO: >10 mg/mL
storage temp.2-8°C
Cas Number799264-47-4
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